SFC Columns

Innovative SFC columns for over 20 years

At Princeton Chromatography we have led the way in developing a series of novel amide, urea and pyridine phases that enhance the capability of the SFC technique by providing increased selectivity and loading capacity. Princeton Chromatography was the first company to develop and market the popular 2-Ethylpyridine phase which was launched in 2001 and later the 4-Ethylpyridine phase. PrincetonSFC 2-Ethylpyridine is non-endcapped and has become the column of choice for achiral SFC analysis of basic compounds. This phase generally requires no addition of amines to the eluent, producing excellent peak shape and reproducibility.


PrincetonSFC analytical columns are available with lengths of 50 to 250 mm and internal diameters of 2.0, 3.0, 4.0 and 4.6 mm. All PrincetonSFC columns are individually quality assured by SFC. Available particle sizes are 3, 5 and 10 μm, with an additional 2.5 μm particle size phase available for the PrincetonSFC 2-Ethylpyridine columns. Pore sizes of 60, 100 and 300Å (for 2-Ethylpyridine phase) are available.

All Princeton semi-preparative and preparative SFC columns are packed using the same high-quality bonded phases as the corresponding analytical columns, making scale up from analytical dimensions seamless and straightforward. Princeton preparative columns are available with internal diameters from 7.8 to 50.0 mm and in lengths from 50 mm to 250 mm. All columns are quality controlled by SFC and individual SFC documentation is included with each column.

Contact us to learn more about how our chromatography experts can support you.